Total body electron beam therapy, also known as total skin electron beam therapy (TSEBT), is an important radiotherapy treatment modality for cutaneous lymphoma, a rare form of lymphoma characterized by widespread involvement of the skin. It is estimated the incidence of cutaneous lymphoma of 1:10000 annually. TSEBT is a highly specialized technique that delivers radiation to the entire surface area of the skin. It was once considered a potentially toxic treatment, but emerging evidence has demonstrated that lower doses of TSEBT can be an effective strategy with excellent outcomes.
The implementation of TSEBT at Pamela Youde Nethersole Eastern Hospital (PYNEH) began in October 2020. This process involved the collaborative efforts of clinical oncologists, physicists, and radiotherapists who worked together in treatment planning, delivery, and dosimetry monitoring. The multidisciplinary approach ensures that the treatment is tailored to each patient's clinical condition and maximizes the therapeutic benefits while minimizing potential side effects.
In an upcoming presentation, the role of TSEBT as part of a multimodality treatment approach in cutaneous lymphoma will be highlighted. The workflow and treatment delivery procedure will be discussed, shedding light on the technical aspects of TSEBT administration. Additionally, the presentation will delve into the clinical outcomes and toxicities observed in six patients who underwent low-dose TSEBT since October 2020.It is hoped to provide insights into its implementation and contributes to the growing body of knowledge of TSEBT and its role in managing cutaneous lymphoma.
